WS12-05Umbilical and fetal cerebral circulation and fetal growth

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Hypoxic regulation of the fetal cerebral circulation.

Fetal cerebrovascular responses to acute hypoxia are fundamentally different from those observed in the adult cerebral circulation. The magnitude of hypoxic vasodilatation in the fetal brain increases with postnatal age although fetal cerebrovascular responses to acute hypoxia can be complicated by age-dependent depressions of blood pressure and ventilation. Acute hypoxia promotes adenosine rel...

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Fetal and neonatal pulmonary circulation.

During fetal life, gas exchange is carried out in the placenta. The lung does not have a physiological role, apart from possible metabolic functions which include secretion of hormones, enzymatic conversion of inactive substances to functional hormones, and degradation of active materials to inactive metabolites. Blood flow through the lungs is quite low during fetal life; most of the systemic ...

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Invited Review HIGHLIGHTED TOPIC Regulation of the Cerebral Circulation Hypoxic regulation of the fetal cerebral circulation

Pearce, William. Hypoxic regulation of the fetal cerebral circulation. J Appl Physiol 100: 731–738, 2006; doi:10.1152/japplphysiol.00990.2005.—Fetal cerebrovascular responses to acute hypoxia are fundamentally different from those observed in the adult cerebral circulation. The magnitude of hypoxic vasodilatation in the fetal brain increases with postnatal age although fetal cerebrovascular res...

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The fetal circulation.

Accumulating data on the human fetal circulation shows the similarity to the experimental animal physiology, but with important differences. The human fetus seems to circulate less blood through the placenta, shunt less through the ductus venosus and foramen ovale, but direct more blood through the lungs than the fetal sheep. However, there are substantial individual variations and the pattern ...

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The fetal circulation

different from the adult circulation. In the fetus, gas exchange does not occur in the lungs but in the placenta. The placenta must therefore receive deoxygenated blood from the fetal systemic organs and return its oxygen rich venous drainage to the fetal systemic arterial circulation. In addition, the fetal cardiovascular system is designed in such a way that the most highly oxygenated blood i...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2000

ISSN: 0960-7692

DOI: 10.1046/j.1469-0705.2000.00009-1-72.x